Table 1. Baseline characteristics of participants with evaluable bacterial sequences, N = 256.
| Characteristic | Overall | HIV- | HIV+ preconceptional ART |
HIV+ no preconceptional ART |
||||
|---|---|---|---|---|---|---|---|---|
| N or median | % or IQR |
N or median | % or IQR |
N or median | % or IQR |
N or median | % or IQR |
|
| Overalla | 256 | 100 | 158 | 61.7 | 55 | 21.5 | 41 | 16.0 |
| Age, years | 27 | (22,32) | 25 | (22,31) | 31 | (27,33) | 25 | (22,29) |
| <20 | 24 | 9.7 | 20 | 13.1 | 0 | 0 | 4 | 10.0 |
| 20–34 | 194 | 78.5 | 114 | 74.5 | 45 | 83.3 | 35 | 87.5 |
| ≥35 | 29 | 11.7 | 19 | 12.4 | 9 | 16.7 | 1 | 2.5 |
| missing | 7 | 5 | 1 | 1 | ||||
| Marital status | ||||||||
| Married or cohabiting | 208 | 82.9 | 128 | 81.5 | 46 | 85.2 | 34 | 85.0 |
| missing | 3 | 1 | 1 | 1 | ||||
| Smoking | 1 | 0.4 | 0 | 0 | 0 | 0 | 1 | 2.5 |
| missing | 4 | 1 | 2 | 1 | ||||
| Alcohol use | 25 | 10.0 | 13 | 8.3 | 6 | 11.3 | 6 | 15.0 |
| missing | 4 | 1 | 2 | 1 | ||||
| BMI, kg/m2 | 23.9 | (21.8,27.0) | 24.2 | (21.9,27.9) | 24.5 | (22.1,26.6) | 22.3 | (20.3,25.4) |
| <18.5 | 9 | 3.6 | 5 | 3.3 | 1 | 1.9 | 3 | 7.5 |
| 18.5–30 | 201 | 81.4 | 121 | 79.1 | 45 | 83.3 | 35 | 87.5 |
| >30 | 37 | 15.0 | 27 | 17.7 | 8 | 14.8 | 2 | 5.0 |
| missing | 7 | 5 | 1 | 1 | ||||
| Gravidity | 3 | (1,4) | 2 | (1,3) | 3 | (2,4) | 3 | (2,3) |
| Parity | 1 | (0,2) | 1 | (0,2) | 2 | (1,3) | 1 | (1,2) |
| Prior PTB | ||||||||
| 0 (nulliparous) | 71 | 27.7 | 55 | 34.8 | 6 | 10.9 | 9 | 22.0 |
| 0 (parous) | 107 | 41.8 | 61 | 38.6 | 31 | 56.4 | 15 | 36.6 |
| 1 or more | 78 | 30.5 | 42 | 26.6 | 18 | 32.7 | 17 | 41.5 |
| EGA at collection, weeks | 18 | (17,19) | 18 | (17,19) | 18 | (17,19) | 18 | (17,19) |
| Multiple gestation | 8 | 3.2 | 5 | 3.2 | 1 | 1.8 | 2 | 4.9 |
| Short Cervix < 2.5 cm | 6 | 2.8 | 2 | 1.5 | 2 | 4.1 | 2 | 6.1 |
| missing | 37 | 23 | 6 | 8 | ||||
| Hemoglobin < 10.5 g/dL | 38 | 21.6 | 20 | 19.2 | 7 | 17.5 | 11 | 34.4 |
| missing | 78 | 54 | 15 | 9 | ||||
| Syphilis reactive | 18 | 7.3 | 9 | 5.9 | 5 | 9.3 | 4 | 10.0 |
| missing | 7 | 5 | 1 | 1 | ||||
| Abnormal urinalysis | 11 | 4.3 | 6 | 3.8 | 2 | 3.6 | 3 | 7.3 |
| missing | 6 | 2 | 3 | 0 | ||||
| Vaginal washing | 81 | 34.8 | 54 | 35.8 | 13 | 31.7 | 14 | 34.2 |
| missing | 21 | 7 | 14 | 0 | ||||
| Sexual intercourse <24 hours | 69 | 29.4 | 53 | 34.6 | 9 | 22.0 | 7 | 17.1 |
| missing | 19 | 5 | 14 | 0 | ||||
| Vaginal pH, mean (±SD) | 5.52 | 0.61 | 5.46 | 0.64 | 5.54 | 0.58 | 5.73 | 0.46 |
| missing | 10 | 5 | 3 | 2 | ||||
| HIV diagnosis timing | ||||||||
| During pregnancy | 0 | 0 | 34 | 82.9 | ||||
| <5 years before pregnancy | 44 | 80.0 | 3 | 7.3 | ||||
| 5+ years before pregnancy | 11 | 20.0 | 4 | 9.8 | ||||
| HIV RNA viral copies/μL | 0 | (0,0) | 12361 | (2956,31358) | ||||
| <40 (undetectable) | 49 | 89.1 | 0 | 0 | ||||
| CD4 cells/mL, n = 19 | 500 | (426,654) | 335 | (242,475) | ||||
| CD4 <200 cells/mL | 1 | 7.7 | 1 | 16.7 | ||||
| missing | 42 | 35 | ||||||
IQR, interquartile range; BMI, body mass index; PTB, preterm birth; EGA, estimated gestational age
a Except for the overall columns, this table excludes 2 HIV-infected participants with unknown ART timing