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. 2019 Oct 2;14(10):e0223435. doi: 10.1371/journal.pone.0223435

Fig 8. Dietary polyphenols of BDPP trended to modulate the upregulation of pro-inflammatory cytokines and chemoattractants induced by IVD injury in DRGs.

Fig 8

Gene expressions (fold change relative to GAPDH and Naïve group) of inflammatory cytokines (tnfα, il-1β, il-2, il-6 and il-10), chemoattractants (ccl2and ccl12), as well as neurotransmitters and receptors (cgrp, tac1 and tacr1) in DRGs collected at (A) 1-week (n = 6 for Naïve, n = 8 for Sham, n = 8 for Injury & n = 7 for BDPP) and (B) 6-week post-op (n = 4 for Naïve, n = 6 for Sham, n = 4 for Injury & n = 6 for BDPP) were determined using real-time qPCR. Cross bars present group mean±SEM values.