The ANN modeled the 2D dose map of the fluence map from EPID. The fluence map EPID of nasopharynx case that was used as input for ANN (a), 2D-dose map modeled by ANN for nasopharynx case (b). The fluence map EPID of prostate case that was used as input for ANN (c), 2D-dose map modeled by ANN for prostate case (d). The blue line depicts the boundaries of the ANN replicated dose. 2D,two-dimensional; ANN, artificial neural network; EPID, electronic portalimaging device.