Skip to main content
. 2019 Oct 2;5(10):eaax3641. doi: 10.1126/sciadv.aax3641

Fig. 4. ATP analogs have little effect on the conformation of the 2CARD domain.

Fig. 4

RIG-I was mixed with RNA, followed by the indicated ATP analog. A one-way analysis of variance (ANOVA) identified an effect of ATP analog on 2CARD ejection (F5,12 = 9.362, P = 0.0008) and a Dunnett’s post hoc test identified adenosine diphosphate (ADP)–AlFx as the only sample significantly different from the +SLR14 sample that lacked ATP analog (*P = 0.0143). Error bars correspond to the SEM across replicate samples.