Table 1.
Analysis platform | Sample analyzed* | Type of alteration detected |
---|---|---|
Exome | 5 cPAC and matching normal | Germline and somatic SNVs, CNVs, and SVs in coding regions |
Amplicon | 61 cPAC and matching normal^, 8 cell lines | Germline and somatic SNVs in 53 cancer genes |
10 cPASC and matching normal, 1 cell line | Germline and somatic SNVs in 53 cancer genes | |
2cPSCC and matching normal, 1 cell line | Germline and somatic SNVs in 53 cancer genes | |
Total | 78 tumor-normal pairs, 10 cell lines |
an additional cell line (OSUK9PADRiley) was analyzed by Sanger sequencing
all matching normal samples were available except one (CCB30381)
cPAC: Canine Pulmonary Adenocarcinoma; cPASC: Canine Pulmonary Adenosquamous Carcinoma; cPSCC: canine Pulmonary Squamous Cell Carcinoma.