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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Clin Cancer Res. 2019 Aug 20;25(19):5866–5877. doi: 10.1158/1078-0432.CCR-19-1145

Table 1.

Genomic analyses performed in primary canine lung cancer.


Analysis platform Sample analyzed* Type of alteration detected
Exome 5 cPAC and matching normal Germline and somatic SNVs, CNVs, and SVs in coding regions
Amplicon 61 cPAC and matching normal^, 8 cell lines Germline and somatic SNVs in 53 cancer genes
10 cPASC and matching normal, 1 cell line Germline and somatic SNVs in 53 cancer genes
2cPSCC and matching normal, 1 cell line Germline and somatic SNVs in 53 cancer genes

Total 78 tumor-normal pairs, 10 cell lines
*

an additional cell line (OSUK9PADRiley) was analyzed by Sanger sequencing

^

all matching normal samples were available except one (CCB30381)

cPAC: Canine Pulmonary Adenocarcinoma; cPASC: Canine Pulmonary Adenosquamous Carcinoma; cPSCC: canine Pulmonary Squamous Cell Carcinoma.