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Unsupervised non-negative matrix factorization based on the 1,000 most variable probes based on the median absolute deviation (MAD). A. Consensus matrices for k=2 to k=7. B. Cophenetic correlation coefficient for k=2 to k=7. C. Methylation profiles of the clusters. D. Survival curves for the methylation derived clusters: M1 (N=16), M2 (N=18) and M3 (N=36).
