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Dissociation constants for the 7 unique VHHs identified. Values represent mean ± standard deviation. Binding was measured using Octet as described in the method section.
| Kd (nM) | ||
|---|---|---|
| VHH name | UBC6e (1-234) | UBC6e(1-197) |
| UBC6e 02 | 80 ± 20 | 60 ± 30 |
| UBC6e 03 | 160 ± 40 | 280 ± 60 |
| UBC6e 05 | 5 ± 2 | 6 ± 2 |
| UBC6e 08 | 900 ± 200 | 600 ± 300 |
| UBC6e 11 | 2200 ± 1500 | 4600 ± 1300 |
| UBC6e 16 | 800 ± 200 | No binding |
| UBC6e 18 | 1000 ± 700 | 1500 ± 600 |
