Table 3.

23S rRNA, gyrA mutations and the range of minimum inhibitory concentration (MIC) values in H. pylori-susceptible and -resistant isolates

Clarithromycin/23S rDNA	Susceptible (n=38), n (%)	Resistant (n=21), n (%)	MIC value (range; mg/L)
No mutation	4 (10.5)	0	≤0.016
A2142G	0	2 (9.5)	32–>256
A2143G	0	19 (90.5)	2–>256
Levofloxacin/gyrA	Susceptible (n=44), n (%)	Resistant (n=15), n (%)	MIC value (range; mg/L)
No mutation	44 (100)	0	<0.002–0.19
N87I (Asn87Ile)	0	2 (13.3)	>32
N87K (Asn87Lys)	0	8 (53.3)	16–>32
D91N (Asp91Asn)	0	2 (13.3)	>32
D91Y (Asp91Tyr)	0	3 (20)	3–12