Table 2.

Efficacy of ICI

Variables(N = 71)	With severe grade CIP (N = 11)	Without severe grade CIP (N = 60)	P‐value
Best treatment effect of ICI			0.47
CR	0 (0)	1 (1.7)
PR	1 (9.1)	20 (33.3)
SD	3 (27.3)	14 (23.3)
PD	7 (63.6)	24 (40.0)
Not comparable†	0 (0)	1 (1.7)
ORR	9.1%	35.6%	0.20
DCR	36.4%	59.3%	0.34

^† One patient had no target‐lesion which could be assessed based on the Response Evaluation Criteria in Solid Tumors version 1.

Data are presented as N (%).

CIP, checkpoint inhibitor pneumonitis; CR, complete response; DCR, disease control rate; ICI, immune checkpoint inhibitor; ORR, overall response rate; PD, progressive disease; PR, partial response; SD, stable disease.