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Sensitivity of different drugs to A549, HCC827 and H1975 cells. (a) Inhibition of three NSCLC cells by apatinib monotherapy. (b) Apatinib combined with pemetrexed, icotinib or osimertinib inhibit proliferation for three NSCLC cells. In the combined group, the concentrations of apatinib for A549, HCC827 and H1975 were as follows: 22, 20 and 8 μmol/L (** P < 0.01).
