Table 2.
Author | Date range | n = x | Definition of SPD | Outcome – graft survival | Comments |
---|---|---|---|---|---|
Dharnidharka [9] | 1987–2003 | 3957 | 0–5 years | 1-year graft survival | EBK GT rate 4% SOK GT rate 3% |
▪ SOK – 81% ▪ EBK – 85% | |||||
3-year graft survival | |||||
▪ SOK – 68% ▪ EBK – 76% | |||||
5-year graft survival | |||||
▪ SOK – 63% ▪ EBK – 71% | |||||
Bhayana [10] | 1998–2006 | 3198 | 0–5 years | 1-year graft survival | EBK GT rate 5% SOK GT rate 3% |
▪ SOK – 81% ▪ EBK – 85% ▪ Adult SCD – 90% ▪ Adult ECD – 83% | |||||
10-year graft survival | |||||
▪ SOK – 53% ▪ EBK – 64% ▪ Adult SCD – 57% ▪ Adult ECD – 40% | |||||
Pelletier [11] | 1993–2002 | 2449 | < 20 kg | 5-year graft survival | HR 0.96 for GL per 1 kg increase in donor weight |
▪ SOK – 55% ▪ EBK – 73% | |||||
Bresnahan [12] | 1988–1995 | 2198 | 0–5 years | 1-year graft survival | SOK + EBK GT rate 10% |
▪ SOK + EBK – 74% | |||||
5-year graft survival | |||||
▪ SOK + EBK – 56% | |||||
Maluf [13] | 2005–2010 | 1531 | < 20 kg | 1-year graft survival | 1-year transplant outcomes by kg weight strata |
▪ SOK – 69% (8 Kg) ▪ EBK – 80% (8 Kg) ▪ SOK – 86% (20 Kg) ▪ EBK – 91% (20 Kg) | |||||
Chesnaye [14] | 1990–2013 | 429 | 0–5 years | 5-year graft survival | Association of donor-recipient age combination on outcomes |
▪ 70% (recipient age 0–3 years) ▪ 75% (recipient age 0–5 years) ▪ 81% (recipient age 6–11 years) ▪ 83% (recipient age 12–19 years) | |||||
Yaffe [15] | 1996–2013 | 167 | 10–20 kg | 1-year graft survival | All into paediatric recipients |
▪ SOK – 90% ▪ EBK – 86% | |||||
5-year graft survival | |||||
▪ SOK – 61% ▪ EBK – 73% | |||||
Winnicki [16] | 2000–2013 | 126 | Not defined | 1-year graft survival | All into paediatric recipients |
▪ EBK – 86% ▪ Adult SCD – 93% | |||||
5-year graft survival | |||||
▪ EBK – 64% ▪ Adult SCD – 69% | |||||
Diaz [17] | 1990–2012 | 100 | Not defined | 12-year graft survival | GT rate 15% |
▪ EBK – 79% ▪ Adult SCD – 69% | |||||
Satterthwaite [18] | 1984–1995 | 91 | 1–4 years | 1-year graft survival | |
▪ SOK – 64% ▪ EBK – 82% | |||||
Thomusch [19] | 1989–2008 | 78 | Not defined | 1-year graft survival | |
▪ EBK – 83% ▪ Adult SCD – 90% | |||||
5-year graft survival | |||||
▪ EBK – 76% ▪ Adult SCD – 78% | |||||
10-year graft survival | |||||
▪ EBK – 74% ▪ Adult SCD – 56% | |||||
Sureshkumar [20] | 1990–2001 | 72 | Not defined | 1-year graft survival | GT rate 13% - Mean age 17 months |
▪ EBK – 82% ▪ Adult LD – 93% | |||||
Gander [21] | 2000–2015 | 60 | 0–6 years | 1-year graft survival | |
▪ All SPD organs – 1 year. GS 81% | |||||
5-year graft survival | |||||
▪ All SPD organs – 5 years. GS 70% | |||||
Strey [22] | 1992–1999 | 56 | 0.50.5–48 months | 1-year graft survival | GT rate 21% - donors < 1 years age (heparinisation used) |
▪ EBK – 78% ▪ Adult DD – 92% | |||||
Sharma [23] | 2000–2011 | 52 | < 10 years old | 5-year graft survival | All into adult recipients |
▪ SOK – 81% ▪ EBK – 94% ▪ Adult SCD – 75% ▪ Adult ECD – 75% | |||||
Borboroglu [24] | 1994–2001 | 48 | 0–2 years | 2-year graft survival | |
▪ SOK – 93% ▪ EBK – 77% | |||||
Dave [5] | 1997–2011 | 47 | < 2 years | 1-year graft survival | No difference compared to older paediatric donors. Median 9 years. PS 100% |
▪ SOK + EBK – 83% | |||||
Bretan [25] | 1993–1996 | 40 | 0–5 years | 1-year graft survival | GT rate 2.5% |
▪ EBK – 100% | |||||
2-year graft survival | |||||
▪ EBK – 85% | |||||
Sui [26] | 2012–2014 | 38 | < 15 kg | 1-year graft survival | All into paediatric recipients |
▪ All SPD organs – 89% ▪ SOK – 96% ▪ EBK – 70% | |||||
Basiri [27] | 2006–2013 | 36 | Not defined | 1-year graft survival | GT rate 5.5% |
▪ EBK + SOK – 90% ▪ Adult DD – 92% | |||||
Hobart [28] | 1990–1997 | 33 | < 4 years | 1-year graft survival | GT rate 15% |
▪ EBK – 87% ▪ Adult DD – 84% | |||||
Mohanka [29] | 2002–2006 | 33 | < 15 kg | 1-year graft survival | All into adult recipients |
▪ SOK – 86% ▪ EBK – 79% | |||||
Salvatierra [30] | 1969–1973 | 32 | 1–9 years | 6-month graft survival | |
▪ SOK – 50% | |||||
Zafarghandi [31] | 2004–2009 | 23 | < 16 years | 1-year graft survival | All into adult recipients |
▪ EBK + SOK – 96% ▪ Adult DD – 91% | |||||
5-year graft survival | |||||
▪ EBK + SOK – 85% ▪ Adult DD – 85% |
GS graft survival, GT graft thrombosis, HR hazard ratio, GL graft loss, LD live donor, DD deceased donor, SOK single organ kidney, EBK en bloc kidney, PS patient survival