Figure 1.

Kinase capturing matrix. (a) Chemical structures of the nine kinase capturing compounds. Amines used for coupling are oriented to the right (b) Heatmap displaying the number of unique identified peptides for each identified kinase using each individual capturing compound alone. Kinases were categorized according to their subfamilies. Pulldowns were performed using a lysate mix of K562, HEK293 and human placenta. The number of identified peptides was used as a proxy to estimate capturing efficacy (see also Supplemental Table 1).