Table 1.
Demographics, clinical ophthalmic assessments and volumetric MRI assessments of glaucoma and healthy control groups.
| Glaucoma (n = 32) | Healthy Control (n = 10) | P-values | Significance | |
|---|---|---|---|---|
| Age (year) | 62.5 ± 1.5 | 64.5 ± 2.9 | 0.527 | ns |
| Sex | 13M, 19F | 3M, 7F | 0.546 | ns |
| Average RNFL thickness (µm) OD | 74.5 ± 2.3 | 88.6 ± 3.5 | 0.011 | * |
| Average RNFL thickness (µm) OS | 74.6 ± 2.3 | 89.0 ± 3.1 | 0.010 | * |
| Optic nerve head C/D OD | 0.66 ± 0.03 | 0.46 ± 0.07 | 0.002 | * |
| Optic nerve head C/D OS | 0.68 ± 0.03 | 0.40 ± 0.08 | 0.001 | * |
| Visual field mean deviation (dB) OD | −3.80 ± 1.09 | −1.17 ± 0.29 | 0.189 | ns |
| Visual field mean deviation (dB) OS | −4.37 ± 0.87 | −0.64 ± 0.18 | 0.023 | * |
| Optic nerve volume (mm3) OD | 429.9 ± 87.8 | 534.7 ± 52.9 | 0.001 | * |
| Optic nerve volume (mm3) OS | 430.9 ± 85.3 | 534.2 ± 51.7 | 0.001 | * |
| V1 grey matter volume (mm3) | 8517.8 ± 1485.8 | 8302.8 ± 2357.8 | 0.730 | ns |
| V2 grey matter volume (mm3) | 13722.9 ± 4837.4 | 16144.7 ± 8231.2 | 0.266 | ns |
Two sample t-test was used to compare between groups for all variables except sex, where chi-squared test was used. *P < 0.05 indicates statistical significance. Data are presented as mean ± standard error. (RNFL: retinal nerve fiber layer; C/D: cup-to-disc ratio; OD: right eye; OS: left eye; ns: not significant).