Table 3.
Multivariable analysis. Variables independently associated with hospital mortality
| Variables | Model without imputation (N = 898) | Model with imputation (N = 1008) | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Direct admission to the ICU from the ED | 0.64 | (0.45 to 0.92) | 0.02 | 0.63 | (0.45 to 0.88) | 0.007 |
| Age > 60 years | 1.47 | (1.04 to 2.10) | 0.03 | 1.47 | (1.05 to 2.04) | 0.02 |
| Disease status | ||||||
| Remission or newly diagnosed | 1.00 | |||||
| Other | 1.49 | (1.08 to 2.06) | 0.01 | 1.52 | (1.12 to 2.07) | 0.008 |
| Allogeneic BMT/HSCT recipient | 2.46 | (1.57 to 3.86) | < 0.0001 | 2.42 | (1.58 to 3.71) | < 0.0001 |
| Charlson (/point) | 1.06 | (0.99 to 1.14) | 0.10 | 1.07 | (1.00 to 1.15) | 0.04 |
| Poor PS (> 2) | 1.88 | (1.30 to 2.72) | < 0.001 | 1.99 | (1.40 to 2.83) | 0.0001 |
| SOFA score (/point) | 1.24 | (1.19 to 1.29) | < 0.00001 | 1.23 | (1.19 to 1.28) | < 0.00001 |
| Reason for ICU admission | ||||||
| Sepsis or septic shock | 1.00 | |||||
| Acute respiratory failure | 2.16 | (1.47 to 3.2) | < 0.001 | 2.11 | (1.45 to 3.06) | < 0.0001 |
| Coma | 1.68 | (0.89 to 3.15) | 0.10 | 1.72 | (0.94 to 3.15) | 0.08 |
| Metabolic disorder or acute kidney injury | 2.05 | (1.17 to 3.56) | 0.01 | 2.12 | (1.24 to 3.62) | 0.006 |
| Other | 2.17 | (1.30 to 3.63) | 0.003 | 2.25 | (1.38 to 3.67) | 0.001 |
BMT bone marrow transplantation, ED emergency department, HSCT hematopoietic stem-cell transplantation, ICU intensive care unit, PS performance status, SOFA Sequential-Related Organ Failure Assessment