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. 2019 Sep 26;10:1241. doi: 10.3389/fphys.2019.01241

TABLE 2.

Quantitative results of the effects among each experimental group demonstrating zebrafish inflammation (n = 10).

Group Concentration (μg/mL) Number of neutrophils (mean ± SE) Anti-inflammatory effects (%)
Control 2 ± 0.29
LPS 18 ± 1.43
Indomethacin 28.6 12 ± 1.00∗∗∗ 33∗∗∗
HLJDD 6.25 14 ± 1.53 22
12.5 11 ± 1.13∗∗∗ 39∗∗∗
25 8 ± 0.96∗∗∗ 56∗∗∗
50 7 ± 0.95∗∗∗ 61∗∗∗
100 10 ± 1.58∗∗∗ 44∗∗∗
Berberine 3.9 16 ± 1.64 11
7.8 14 ± 1.00 22
15.6 12 ± 0.73∗∗∗ 33∗∗∗
31.25 9 ± 1.05∗∗∗ 50∗∗∗
62.5 7 ± 0.88∗∗∗ 61∗∗∗
Baicalin 15.6 17 ± 1.07 6
31.25 13 ± 0.40∗∗∗ 28∗∗∗
62.5 10 ± 0.90∗∗∗ 44∗∗∗
125 9 ± 0.73∗∗∗ 50∗∗∗
250 8 ± 0.54∗∗∗ 56∗∗∗
Geniposide 31.25 18 ± 1.34 0
62.5 15 ± 1.23 17
125 14 ± 0.70 22
250 13 ± 1.62 28
500 12 ± 0.96∗∗ 33∗∗

P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001, drug treatment group (or positive group) compared with LPS group.