TABLE 2.
Quantitative results of the effects among each experimental group demonstrating zebrafish inflammation (n = 10).
| Group | Concentration (μg/mL) | Number of neutrophils (mean ± SE) | Anti-inflammatory effects (%) |
| Control | – | 2 ± 0.29 | – |
| LPS | – | 18 ± 1.43 | – |
| Indomethacin | 28.6 | 12 ± 1.00∗∗∗ | 33∗∗∗ |
| HLJDD | 6.25 | 14 ± 1.53 | 22 |
| 12.5 | 11 ± 1.13∗∗∗ | 39∗∗∗ | |
| 25 | 8 ± 0.96∗∗∗ | 56∗∗∗ | |
| 50 | 7 ± 0.95∗∗∗ | 61∗∗∗ | |
| 100 | 10 ± 1.58∗∗∗ | 44∗∗∗ | |
| Berberine | 3.9 | 16 ± 1.64 | 11 |
| 7.8 | 14 ± 1.00∗ | 22∗ | |
| 15.6 | 12 ± 0.73∗∗∗ | 33∗∗∗ | |
| 31.25 | 9 ± 1.05∗∗∗ | 50∗∗∗ | |
| 62.5 | 7 ± 0.88∗∗∗ | 61∗∗∗ | |
| Baicalin | 15.6 | 17 ± 1.07 | 6 |
| 31.25 | 13 ± 0.40∗∗∗ | 28∗∗∗ | |
| 62.5 | 10 ± 0.90∗∗∗ | 44∗∗∗ | |
| 125 | 9 ± 0.73∗∗∗ | 50∗∗∗ | |
| 250 | 8 ± 0.54∗∗∗ | 56∗∗∗ | |
| Geniposide | 31.25 | 18 ± 1.34 | 0 |
| 62.5 | 15 ± 1.23 | 17 | |
| 125 | 14 ± 0.70 | 22 | |
| 250 | 13 ± 1.62∗ | 28∗ | |
| 500 | 12 ± 0.96∗∗ | 33∗∗ |
∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001, drug treatment group (or positive group) compared with LPS group.