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. 2019 Sep 26;10:664. doi: 10.3389/fendo.2019.00664

Figure 1.

Figure 1

(A,B) Effect plots of the complex interdependency between FT3, FT4, and TSH. (A) shows the relationship between FT3 and TSH, examined by treatment category, after adjusting for FT4 concentrations, gender, age, and BMI. (B) The resulting equilibria between FT4 and TSH (as surrogate markers for setpoints), associated with treatment category and FT3 concentrations in a significant interaction (Pillai-test p < 0.001, see Results for details). The three treatment categories refer to patients with thyroid carcinoma (1), autoimmune thyroiditis (2), and benign goiter (3). f indicates female, and m male gender. Cat, disease category. Regression lines are surrounded by the 95% confidence limit.