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. 2019 Aug 21;10(10):2045–2049. doi: 10.1111/1759-7714.13177

Figure 2.

Figure 2

Following administration of the fourth and final dose of nivolumab, the patient's creatine kinase (CK) level was 2934 U/L (normal level, NR < 187). Intravenous corticosteroids (methylprednisolone 1 mg/kg/day) were administered and the CK level returned to its normal range by the 32nd day. Pyridostigmine was administered to relieve the patient's remaining symptoms at a dose of 30 mg three times a day for six days and this was increased to 60 mg three times a day. Intravenous steroids were tapered to oral prednisolone at 40 mg twice a day. PRD, prednisolone.