Table 1.
Minimal inhibitory concentration (MIC) in µg/ml for four peptides against several Gram-positive and Gram-negative bacteria. All MICs were performed in Mueller–Hinton bouillon at least three times, and data are stated as the modal value. MRSA stands for methicillin-resistant Staphylococcus aureus and VRE for vancomycin-resistant Enterococcus faecalis.
| Peptide/bacteria | Staphylococcus aureus ATCC 29213 |
MRSA | Escherichia coli
ATCC 25922 |
Escherichia coli
UB1005 |
Escherichia coli
68610Y |
VRE NCTC 12203 |
Enterococcus faecalis ATCC 29212 |
Staphylococcus epidermidis |
|---|---|---|---|---|---|---|---|---|
| T14L | 0.5 | 0.5 | 2 | 4 | 2 | 1 | 1 | <0.25 |
| T14D | 1 | 1 | 2 | 2 | 2 | 1 | 1 | <0.25 |
| T69L | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 0.5 |
| T69D | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 0.5 |