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. 2019 Sep 26;10:871. doi: 10.3389/fgene.2019.00871

Table 5.

Influence of clinical confounding factors$.

Odds ratio§ 95 % CI P value Adjusted P value#
Acute rejection (AR)
HLA mismatch ≥ 3 alleles vs HLA mismatch <3 alleles 12.14 1.76, 525.21 0.0027 0.019
Delayed graft function (DGF)
Graft from deceased vs
living donor
7.15 2.23, 30.46 0.0001 0.0008
Estimate* 95 % CI P value Adjusted P value#
eGFR at discharge
Graft from deceased vs living donor -17.00 -24.00, -9.00 0.00001 0.0001

CI, confidence interval; HLA, human leukocyte antigen; eGFR, estimated glomerular filtration rate.

$Table shows only confounders which were significantly associated with one of the outcome measures AR, DGF, or eGFR. Confounders tested: HLA alleles, vPRA, virtual panel reactive antibodies, donor source, previous transplantation, valgancyclovir therapy, AB0 compatibility, type of induction therapy.

*Difference in location (Wilcoxon rank sum test) from eGFR at discharge (mL/min).

§Fisher test.

#Adjusted for multiple comparisons according to Holm’s procedure.