Table 3.
Allelic and Genotypic Analysis in ADHD-alone (n = 295) and Controls (n = 963).
| SNP | A1 | A2 | Allelic comparison | Genotypic comparison | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| A1/A2 in case: control | OR (95% CI) | P | Additive | Dominant | Recessive | ||||||
| A1A1/A1A2/A2A2 in case: control | P | OR (95% CI) | P | OR (95% CI) | P | ||||||
| rs11605461 | A | G | 456/126: 1536/390 |
0.92 (0.73–1.15) |
0.464 | 174/108/9: 614/308/41 | 0.213 | ||||
| rs11215407 | A | G | 380/208: 1156/770 |
1.22 (1.00–1.48) |
0.045 | 127/126/41: 347/462/154 | 0.085 | ||||
| rs7482812 | C | T | 213/373: 719/1207 |
0.96 (0.79–1.16) |
0.666 | 41/131/121: 130/459/374 |
0.670 | ||||
| rs10790068 | C | T | 404/184: 1321/605 |
1.00 (0.82–1.23) |
0.956 | 138/128/28: 460/401/102 |
0.789 | ||||
| rs10458969 | A | G | 165/421: 511/1411 |
1.08 (0.88–1.33) |
0.453 | 23/119/151: 64/383/514 |
0.722 | ||||
| rs17118125 | A | G | 473/115: 1531/395 |
1.06 (0.84–1.34) |
0.616 | 187/99/89: 609/313/41 |
0.481 | ||||
| rs10891819 | G | T | 418/168: 1353/565 |
1.04 (0.85–1.27) |
0.713 | 139/140/14: 485/383/91 |
0.008 | 1.12 (0.87–1.46) |
0.384 | 0.48 (0.27–0.85) |
0.012 |
| rs10502204 | C | T | 200/388: 628/1298 |
1.07 (0.88–1.30) |
0.525 | 32/136/126: 96/436/431 |
0.812 | ||||
| rs7952231 | G | T | 142/428: 500/1380 |
0.92 (0.74–1.14) |
0.423 | 17/108/160: 68/364/508 |
0.697 | ||||
| rs220860 | A | C | 469/119: 1545/377 |
0.96 (0.76–1.21) |
0.740 | 191/87/16: 617/311/33 |
0.236 | ||||
| Logistic regression with covariates a | |||||||||||
| rs10891819 | G | T | 418/168: 1353/565 |
1.02 (0.80–1.29) |
0.895 | 139/140/14: 485/383/91 |
0.042 | 1.19 (0.88–1.62) |
0.258 | 0.55 (0.29–1.04) |
0.067 |
ADHD-alone, ADHD subjects without any comorbidity; OR: odd ratios; 95% CI: 95% confidence interval; the ancestry alleles were bolded.
a
Age, sex, and the 10 principal components from the multidimensional scaling procedure as covariates.