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. 2019 Aug 19;15(10):2240–2255. doi: 10.7150/ijbs.35356

Figure 5.

Figure 5

The alterations of miR-27a levels of the recipient WS1 cells after culture with exosomes and the effects of the redox status of recipient WS1 cells. (A) The dependence of the alterations of the miR-27a levels of the recipient WS1 cells on the culture time with the 3 h exosomes. (B) The alterations of the miR-27a levels of the recipient WS1 cells after culture with the 3 h exosomes from the HaCaT cells pre-transfected with miR-27a inhibitors and NC. (C) No increase in the miR-27a levels of the recipient WS1 cells overexpressing SOD2 was observed after culture with the 3 h exosomes from irradiated HaCaT cells. (D) No elevation of the intracellular ROS levels was observed in the recipient WS1 cells overexpressing SOD2 after culture with the 3 h exosomes from irradiated HaCaT cells. (E) No significant reduction in the migration rate was observed in the recipient WS1 cells overexpressing SOD2 after culture with the 3 h exosomes from irradiated HaCaT cells. All the data represent the means ± SEM from three independent experiments (n=3). *P<0.05, **P<0.01 and ***P<0.001 compared with the relative control. NS, not significant.