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(A) Van Gieson staining of undecalcified sections, red indicates bone tissue and black indicates the residual scaffold material in defect site. (C, E) Histological analysis of decalcified sections: red arrow indicates new vessels and new bone, black arrow indicates graphene oxide. (B, D, F) Quantitative analysis of newly bone tussues, neovessel and OCN. (* and # represent p < 0.05 when compared with MBG, MBG-LGO, respectively).
