Figure 4.

Kaplan-Meier survival analysis to evaluate the independence of the six-mRNA signature from histological grade, TNM stage and tumor subdivision of pancreas. The patients from combined datasets were stratified into subgroups. The six-mRNA signature was applied to the low histological grade patients (A), high histological grade patients (B), TNM stage II and III patients (C), patients with tumor subdivision in head (D), body (E) and tail (F) of pancreas, separately. The number of patients at risk was listed below the survival curves. The tick marks on the Kaplan-Meier curves represent the censored subjects. The differences between the two curves were determined by the two-sided log-rank test.