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Upregulation of FZD2 in CAL-27 cells promoted cells migration and invasion in vitro. After transfected with plasmid, the cell motility and invasiveness were boosted, as detected by wound healing (A) and transwell assays (B, P<0.005 by One-Way ANOVA followed by Tukey's multiple Comparison test), the representative images of transwell inserts coated without (upper panel) or with (lower panel) matrigel.
