CRAMP improves cardiac function in diabetic mice. A. CRAMP level in serum and myocardium after 1, 2, 4 weeks of CRAMP injection (8mg/kg/d)(n=6, *P<0.05 vs. CON). B. Body weight and blood glucose of mice at 0, 1, 2, 3, 4 months after STZ injection (n=10). C. Heart weight, lung weight, heart weight to body weight ratio, and heart weight to tibia length ratio in diabetic mice treated with CRAMP (n=10). D. Representative image of the heart with H&E staining and wheat germ agglutinin (WGA) staining (n=6). E. The cell surface area of cardiomyocytes in heart tissue (n=100+ cells per group). *P<0.05 vs the corresponding Sham; #P<0.05 vs. vehicle-DCM.