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CRAMP inhibits cardiac fibrosis in diabetic mice. A and C. Representative image of the heart with Picro-Sirius red (PSR) staining and Immunohistochemical staining of collagen III (n=6). B. Quantification of the total collagen volume in the indicated group. D. PCR analysis of fibrotic markers (collagen I, collagen III, TGFβ, CTGF) in diabetic heart tissue (n=6). *P<0.05 vs the corresponding Sham; #P<0.05 vs vehicle-DCM.
