Skip to main content
. 2019 Sep 7;15(11):2393–2407. doi: 10.7150/ijbs.35736

Table 3.

Echocardiography and hemodynamics Parameters in diabetic mice after injected with Ad-shAMPKα1 and treated with CRAMP.

Vehicle-CON (n=8) CRAMP-CON (n=8) Vehicle-DCM (n=8) CRAMP -DCM (n=8)
LVEF (%) 61.8±3.9 62.1±3.6 38.6±3.1* 38.5±4.7*
LVFS (%) 30.6±1.7 29.8±3.9 14.9±2.5* 15.4±1.9*#
HR (bpm) 485±46 496±50 496±69 486±53
dp/dt max (mmHg/s) 8394±481 8497±561 3745±438* 3776±439*
dp/dt min(mmHg/s) -8975±766 -8736±819 -3851±807* -3945±629*
Tau (Weiss; ms) 9.28±1.34 8.87±1.37 22.23±3.19* 23.13±2.02*

LVEF, left ventricular ejection fraction; LVFS, left ventricular ejection of shortening; HR, heart rate; dp/dtmax, maximal rate of pressure development; dp/dtmin, maximal rate of pressure decay; Tau, time constant of LV pressure decay *P<0.05 for difference from corresponding sham group. #P<0.05 vs vehicle-DCM group.