Table 4.
Median values and interquartile range of cytokines relative expression in PBMCs from ASD patients and their parents and in healthy controls.
| TNF-α | INF-γ | IL-10 | IL-8 | IL-1β | IL-6 | ||
|---|---|---|---|---|---|---|---|
| Children | HC | 0.25 (0.15–0.29)* | 1.35 (0.40–2.91) | 2.02 (1.41–7.95) | 8.81 (5.79–17.77) | 0.79 (0.43–3.82) | 13.32 (2.54–26.24) |
| ASD | 251.17 (101.04–1153.65) | 40.46 (27.62–85.81) | 2603.20 (1197.99–3847.43) | 31.77 (23.46–42.07) | 0.81 (0.20–1.73) | 11.22 (6.87–21.04) | |
| Mothers | HC | 2.26 (0.97–4.57) | 11.38 (2.85–48.91) | 2.37 (1.52–4.31) | 39.64 (33.66–149.58) | 5.99 (2.28–17.66) | 8.42 (3.28–23.07) |
| ASD | 1134.42 (459.67–4946.93) | 144.42 (116.04–319.27) | 1178.35 (651.34–3023.56) | 60.46 (28.40–98.24) | 3.19 (1.68–8.32) | 9.83 (5.81–13.88) | |
| Fathers | HC | 2.94 (2.19–4.16) | 90.62 (31.40–186.71) | 2.44 (1.36–8.11) | 48.92 (24.92–89.66) | 1.05 (0.75–1.56) | 5.92 (2.70–9.95) |
| ASD | 0.33 (0.26–0.77) | 143.18 (96.82–203.19) | 41.46 (28.75–61.57) | 19.38 (12.54–54.86) | 1.61 (1.24–2.34) | 12.44 (4.22–18.95) |
*
Median values (IQR).