Table 1.—
Definite PTCS (n = 61) |
Probable PTCS (n = 10) |
Elevated OP without Papilledema (n = 31) |
Normal OP (reference) (n = 25) |
P-value | |
---|---|---|---|---|---|
Age in years (median, IQR) | 13.6(10.5–16.3) | 11.5(8.4–13.9) | 14.7 (10.6–16.2) | 14.2(11.0–15.4) | .37 |
Female | 41 (67.2%) | 6 (60%) | 19 (61.3%) | 16 (64%) | .91 |
Race | .17 | ||||
Asian | 0 | 0 | 1 | 1 | |
African American | 15 | 0 | 7 | 3 | |
Caucasian | 39 | 10 | 23 | 20 | |
Not Specified | 7 | 0 | 0 | 1 | |
Opening pressure in cm CSF (median, IQR)* | 39 (35–49) | 24 (21–26)* | 35 (31–37) | 23 (18–25)* | Overall P < .001; Definite PTCS vs Probable, Elevated OP, & Normal OP, P < .001; Elevated OP vs Normal OP P < .001 |
BMI Z-score (median, IQR) | 1.6(0.8–2.1) | 1.6 (0.7–1.8) | 1.2(0.8–1.7) | 0.5 (−0.1 – 1.2) | Overall P = .017; Definite PTCS vs Normal OP, P = .006; Elevated OP vs Normal OP, P = .004 |
P-values are from Fisher’s exact test to compare frequencies and Kruskal–Wallis or Mann–Whitney test to compare medians of continuous variables.
Three subjects in the Probable PTCS group and 5 in the Normal OP group had opening pressure between 25 and 28 cm but were classified as Normal OP because the subject was either sedated and/or obese.