TABLE 1.

Estimated fold-difference of expression levels of cellular activation/exhaustion markers between HLA-DR+ and HLA-DR− CD4+ memory T-cells.

Cellular marker	Years on ART	Fold-difference (HLA-DR+ vs. HLA-DR−)	95% CI		p-value
			Lower	Upper
CCR5	3	6.36	3.76	10.77	<0.001
	5	5.74	3.72	8.87	<0.001
	10	4.44	3.27	6.02	<0.001
	15	3.43	2.26	5.21	<0.001
LAG-3	3	0.368	0.240	0.565	<0.001
	5	0.372	0.261	0.530	<0.001
	10	0.382	0.298	0.489	<0.001
	15	0.391	0.279	0.550	<0.001
PD-1	3	1.97	1.63	2.38	<0.001
	5	1.95	1.67	2.28	<0.001
	10	1.91	1.72	2.13	<0.001
	15	1.88	1.62	2.18	<0.001
Tim-3	3	1.80	0.82	3.95	0.143
	5	2.03	1.06	3.89	0.032
	10	2.76	1.75	4.35	<0.001
	15	3.74	2.01	6.97	<0.001