Table 2.
Group parameters at baseline.
| Parameter | Group A | Group B | P | ||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age (years) | 64.1 | 5.8 | 62.9 | 7.2 | 0.465 |
| Sex ratio (M/F) | 16/14 | 16/14 | |||
| Disease duration (months) | 38.73 | 1.53 | 35.53 | 1.65 | 0.929 |
| MD (dB) | −6.51 | 2.65 | −6.39 | 2.03 | 0.850 |
| RNFL (µm) | 72.9 | 7.3 | 73.3 | 4.9 | 0.785 |
| RNFL Sup (µm) | 86.2 | 7.3 | 87.4 | 5.9 | 0.515 |
| RNFL Inf (µm) | 94.6 | 7.5 | 95.4 | 6.9 | 0.673 |
| RNFL Nas (µm) | 70.8 | 8.8 | 68.7 | 6.5 | 0.305 |
| RNFL Temp (µm) | 68.1 | 8.9 | 66.3 | 6.5 | 0.373 |
| GCC (µm) | 73.8 | 7.5 | 74.6 | 5.2 | 0.626 |
| GCC Sup (µm) | 75.6 | 7.7 | 75.9 | 5.4 | 0.839 |
| GCC Inf (µm) | 71.9 | 8.0 | 73.2 | 5.3 | 0.457 |
Statistical comparison of demographical data and optic nerve parameters in group A (patients assuming citicoline) and group B (controls), before starting therapy with citicoline. MD, mean deviation measured with standard automatic perimetry (SAP); RNFL, overall retinal nerve fiber layer thickness; RNFL Sup, superior retinal nerve fiber layer thickness; RNFL Inf, inferior retinal nerve fiber layer thickness; RNFL Nas: nasal retinal nerve fiber layer thickness; RNFL Temp, temporal retinal nerve fiber layer thickness; GCC, overall ganglion cell complex thickness; GCC Sup, superior ganglion cell complex thickness; GCC Inf, inferior ganglion cell complex thickness measured with ocular coherence tomography (OCT); p: Student t-test significance.