Table 4.

Parameter analysis of both groups over the follow-ups.

Paired Student’s t-test comparison
Parameter	Follow-up comparison	Group A			Group B
		Variation	T	p <	Variation	t	p <
MD	0 vs. 6 months	−0.496	12.690	0.001	−0.751	12.028	0.001
	6 vs. 12 months	−0.131	1.620	0.116	−0.816	12.827	0.001
	12 vs. 18 months	−0.119	2.200	0.036	−0.682	10.784	0.001
	18 vs. 24 months	−0.064	1.316	0.199	−0.639	9.531	0.001
RNFL	0 vs. 6 months	−1.738	9.166	0.001	−5.030	20.137	0.001
	6 vs. 12 months	−0.741	5.680	0.001	−3.362	4.920	0.001
	12 vs. 18 months	−0.276	2.692	0.012	−4.476	37.065	0.001
	18 vs. 24 months	−0.144	2.468	0.020	−4.676	37.439	0.001
RNFL Sup	0 vs. 6 months	−1.594	9.114	0.001	−4.500	16.430	0.001
	6 vs. 12 months	−0.748	5.478	0.001	−4.055	28.439	0.001
	12 vs. 18 months	−0.277	2.445	0.021	−4.491	35.957	0.001
	18 vs. 24 months	−1.396	2.524	0.017	−4.858	52.242	0.001
RNFL Inf	0 vs. 6 months	−1.504	11.967	0.001	−4.511	25.876	0.001
	6 vs. 12 months	−0.749	7.200	0.001	−4.245	22.547	0.001
	12 vs. 18 months	−0.213	2.151	0.040	−4.542	35.663	0.001
	18 vs. 24 months	−0.225	2.633	0.013	−4.811	43.296	0.001
RNFL Nas	0 vs. 6 months	−1.595	8.190	0.001	−4.530	21.142	0.001
	6 vs. 12 months	−0.815	5.591	0.001	−4.160	27.324	0.001
	12 vs. 18 months	−0.176	2.215	0.035	−4.273	29.209	0.001
	18 vs. 24 months	−0.252	2.510	0.018	−4.865	38.397	0.001
RNFL Temp	0 vs. 6 months	−1.843	11.391	0.001	−4.538	21.436	0.001
	6 vs. 12 months	−0.726	5.899	0.001	−3.808	19.414	0.001
	12 vs. 18 months	−0.147	0.929	0.361	−4.319	24.487	0.001
	18 vs. 24 months	−0.170	2.255	0.032	−4.661	52.818	0.001
GCC	0 vs. 6 months	−1.532	10.125	0.001	−4.541	22.862	0.001
	6 vs. 12 months	−1.058	6.648	0.001	−4.552	20.706	0.001
	12 vs. 18 months	−0.162	2.290	0.029	−4.472	37.441	0.001
	18 vs. 24 months	−0.146	2.579	0.015	−4.928	39.883	0.001
GCC Sup	0 vs. 6 months	−1.149	7.218	0.001	−3.877	14.240	0.001
	6 vs. 12 months	−0.874	5.306	0.001	−3.987	18.143	0.001
	12 vs. 18 months	−0.270	2.573	0.015	−4.328	22.581	0.001
	18 vs. 24 months	−0.164	2.368	0.025	−4.785	40.536	0.001
GCC Inf	0 vs. 6 months	−1.329	2.467	0.020	−5.268	18.620	0.001
	6 vs. 12 months	−1.319	3.200	0.003	−5.101	11.989	0.001
	12 vs. 18 months	−0.383	2.604	0.014	−4.628	25.836	0.001
	18 vs. 24 months	−0.205	1.535	0.136	−5.026	31.681	0.001

Statistical analysis of the differences between evaluated parameters from baseline to 24 months’ follow-up. MD, mean deviation measured with standard automatic perimetry (SAP); RNFL, overall retinal nerve fiber layer thickness; RNFL Sup, superior retinal nerve fiber layer thickness; RNFL Inf, inferior retinal nerve fiber layer thickness; RNFL Nas, nasal retinal nerve fiber layer thickness; RNFL Temp, temporal retinal nerve fiber layer thickness; GCC: overall ganglion cell complex thickness; GCC Sup, superior ganglion cell complex thickness; GCC Inf, inferior ganglion cell complex thickness measured with ocular coherence tomography (OCT). p, Paired Student t-test significance (values < 0.05 in bold; values < 0.005 in bold on gray).