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. 2019 Aug 1;23(5):667–676. doi: 10.1007/s40291-019-00421-1

Table 3.

Saliva analysis

Variable Day
0 7 14 21 35
Total protein (μg/mL)
 Mean ± SD (na) 1361 ± 758.6A (18) 1188 ± 557.6A (18) 1208 ± 680.1A (18) 855.1 ± 474.3A (18) 1286 ± 940.6A (15)
 95% CI for the mean 984.4–1738 911.1–1466 869.5–1546 483.5–1227 765–1807
Albumin (μg/mL)
 Mean ± SD (na) 29.4 ± 11.2A (18) 29.5 ± 13.2A (18) 31.8 ± 14.4A (18) 37.8 ± 11.2A (17) 31.8 ± 13.6A (18)
 95% CI for the mean 23.8–34.9 22.9–36 24.7–39 32.1–43.6 25–38.7
Chitinase (ΔFt)
 Mean ± SD (na) 152.9 ± 85.6A (15) 148.1 ± 99.7A (16) 154.2 ± 105.2A (16) 203.4 ± 115.2A (16) 159.8 ± 98.6A (16)
 95% CI for the mean 105.5–200.3 95.0–201.2 98.1–210.3 142.1–264.8 107.3–212.4
Protease (ΔFt)
 Mean ± SD (na) 33.0 ± 32.0A (17) 40.5 ± 32.2A (14) 49.5 ± 34.2B (13) 55.7 ± 29.0C (15) 40.7 ± 39.7B (15)
 95% CI for the mean 16.5–49.4 22–59.1 28.4–69.7 39.7–71.8 18.7–62.7

Different capital letters in a row indicate statistical differences. The p value was adjusted by the number of comparisons

CI confidence interval, SD standard deviation, ΔF/Δt protease and chitinase activity measured by increase of fluorescence in time

aNumber of samples assayed for the respective variable out of the total sample population of 18 participants