Table 5.
Results of mixed-effects linear regression of the clinical outcome ‘chitinase activity’ as a function of time, mean gingival inflammation over time and mean gingival inflammation at day − 14
| Explanatory variables | Chitinase activity | |||||
|---|---|---|---|---|---|---|
| Total sample (n = 18) | ‘Fast’ responders (n = 7) | ‘Slow’ responders (n = 11) | ||||
| Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | |
| Time (days) (reference: day 0) | 0.938 | 0.663 | 0.701 | |||
| + 7 | − 0.27 (− 0.69 to 0.13) | − 0.35 (− 1.12 to 0.43) | − 0.27 (− 0.78 to 0.23) | |||
| + 14 | − 0.31 (− 1.21 to 0.60) | − 0.53 (− 1.75 to 0.70) | − 0.48 (− 1.64 to 0.67) | |||
| + 21 | − 0.17 (− 1.20 to 0.86) | 0.02 (− 1.12 to 1.16) | − 0.61 (− 2.20 to 0.97) | |||
| + 35 | − 0.07 (− 0.76 to 0.61) | 0.08 (− 0.52 to 0.68) | − 0.27 (− 1.28 to 0.75) | |||
| Gingival inflammation | 0.10 (− 0.47 to 0.66) | 0.974 | 0.26 (− 0.30 to 0.83) | 0.829 | 0.21 (− 0.65 to 1.08) | 0.715 |
| Gingival inflammation (day − 14) | − 0.05 (− 0.34 to 0.23) | 0.897 | − 0.01 (− 0.30 to 0.26) | 0.989 | − 0.19 (− 1.72 to 1.34) | 0.905 |
The coefficient denotes the mean difference of the chitinase activity outcome given the explanatory variables included in the model. The analysis was adjusted by protein level
CI confidence interval