Table 1.
Basic characteristics of patients with dyslipidemia before and after treatment with statins and of control subjects. Data are given as median (min–max).
| Control subjects (n = 20) | Before treatment with statins (n=30) | After treatment with statins (n=30) | P valuea | P valueb | P valuec | |
|---|---|---|---|---|---|---|
| BMI (kg/m2) | 24.00 (20.00–27.00) | 28.56 (22.00–40.40) | 28.11 (22.40–39.95) | <0.001 | <0.001 | <0.05 |
| WHR | 0.80 (0.70–1.10) | 0.87 (0.76–1.10) | 0.88 (0.75–1.13) | 0.160 | 0.128 | 0.944 |
| Fasting glucose (mg/dL) | 83.50 (71.00–115.00) | 97.00 (83.00–142.00) | 98.00 (85.00–131.00) | <0.001 | <0.001 | 0.688 |
| Triglycerides (mg/dL) | 98.00 (35.00–390.00) | 147.55 (55.00–619.00) | 112.00 (50.10–435.50) | <0.05 | 0.247 | <0.001 |
| Total cholesterol (mg/dL) | 165.50 (145.00–265.00) | 290.35 (177.00–461.00) | 192.25 (136.00–302.00) | <0.001 | <0.05 | <0.001 |
| LDL-cholesterol (mg/dL) | 97.10 (32.89–177.50) | 196.71 (67.00–380.40) | 110.60 (64.80–231.60) | <0.001 | 0.406 | <0.001 |
| HDL-cholesterol (mg/dL) | 46.65 (29.30–85.60) | 49.00 (26.00–95.30) | 54.20 (29.30–84.00) | 0.620 | <0.05 | <0.01 |
| AST (u/L) | 24.00 (10.00–47.00) | 17.00 (10.60–23.00) | 17.00 (6.00–38.90) | <0.001 | <0.01 | 0.577 |
| ALT (u/L) | 21.00 (7.00–52.00) | 16.00 (9.80–39.00) | 17.00 (9.00–45.40) | 0.207 | 0.097 | 0.527 |
ALT: alanine aminotransferase; AST: aspartate aminotransferase; BMI: body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein; WHR: waist-to-hip ratio.
ap value when the comparisons are between the control and before treatment with statin values (Mann–Whitney U test).
bp value when the comparisons are between the control and after treatment with statin values (Mann–Whitney U test).
cp value when the comparisons are between the before treatment and after treatment with statin values (Wilcoxon test).