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. 2019 Mar 12;39(10):1936–1948. doi: 10.1177/0271678X19836117

Figure 1.

Figure 1.

Spontaneous hydrocephalus occurs in SHRs at seven weeks of age. (a) Representative T2-weighted MRI images showing ventricular enlargement in SHRs at week 7 compared with age-matched WKY rats. (b) Quantification of ventricular volume on T2 images at weeks 4, 5 and 7. Values are means ± SD, n = 6; #P < 0.01 compared with WKY group. (c) MRI T2 showing evidence of the aqueduct and 4th ventricular enlargement in SHRs at week 7. (d) SHRs had significant higher systolic blood pressure (SBP) and mean arterial pressure (MAP) than WKY rats at weeks 5, 6 and 7. #P < 0.01 compared with WKY group, n = 6.