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. 2019 Mar 12;39(10):1936–1948. doi: 10.1177/0271678X19836117

Figure 7.

Figure 7.

Cell death in the choroid plexus and ventricular wall damage were alleviated by minocycline. (a) Examples of TUNEL staining in the choroid plexus in SHRs treated with vehicle or 10 or 20 mg/kg minocycline. Note the reduced prevalence of TUNEL-positive cells with minocycline treatment. Quantification of the number of TUNEL-positive cells in the choroid plexus (at level 1). Values are #P < 0.01 compared with SHR + vehicle group; n = 9. Scale bar = 50 μm (low magnification) and 20 μm (high magnification). (b) Quantification of ventricular damage in the three groups. Both minocycline groups had reduced ventricular wall damage compared to the vehicle group. Values are means ± SD, #P < 0.01 compared with SHR + vehicle group, n = 9.