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. 2019 Sep 26;10:1131. doi: 10.3389/fphar.2019.01131

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Copyright © 2019 Ceprián, Vargas, García-Toscano, Penna, Jiménez-Sánchez, Achicallende, Elezgarai, Grandes, Hind, Pazos and Martínez-Orgado

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between immunohistochemical and neurobehavioral studies. Linear correlation between MBP staining intensity and different neurobehavioral test performed 30 days after a hypoxic-ischemic insult induced in P7–10 Wistar rats or a similar period in control rats. (A) Correlation between hemiparesis as assessed by the cylinder rearing test (CRT) and MBP intensity in White Matter (corpus callosum, CC); Spearman’s correlation: R = 0.396, t = 2.58, p = 0.013. (B) Correlation between memory impairment as assessed by novel object recognition test (NOR) and MBP intensity in cortex; Spearman’s correlation: R = 0.443, t = 2.57, p = 0.015).