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. 2019 Aug 28;10(21):5244–5255. doi: 10.7150/jca.30143

Figure 3.

Figure 3

Effects of SN50 on inhibition of stemness of H460 cells induced by proinflammatory cytokines by BrMC. In presence (+) or absence (-) of SN50, NF-κB signaling in H460 CSCs was regulated and inhibition of BrMC was determined. Stemness appearance of CSCs were evaluated by sphere forming assay (A~E) and colony forming assay (F~J). Expressions of CD133, CD44, Bmi1 and Oct4 as well as NF-κBp65 and FoxM1 were analyzed by western blot (K). *P<0.05, vs untreated cells; #P<0.05, vs treated cells by SN50 (10.0 μmol/L).