TABLE 1.
Patient | Age (y) | Sex | Histogenesis | Grade | Location | Surgery | Microsatellite instability | Pretreatment | Status |
---|---|---|---|---|---|---|---|---|---|
Skeletal sarcomas | |||||||||
1 | 8 | M | Osteosarcoma | High | Femur | Resection | Chemo | CDFS for 6 mo | |
2 | 48 | M | Osteosarcoma | High | Tibia | Resection | Chemo | CDFS for 4 mo | |
3 | 69 | M | Osteosarcoma | High | Femur | Amputation | D1S158, D11S861, D7S594, D17S786, D5S107 | Chemo | DWD after 11 mo |
4 | 53 | F | Osteosarcoma | Low | Femur | Resection | None | CDFS for 6 mo | |
5 | 60 | M | Hemangiopericytoma | Low | Scapula | Resection | DM | None | CDFS for 27 mo |
6 | 47 | M | Chondrosarcoma | High | Femur | Amputation | D13S170 | None | DWD after 24 mo |
Soft tissue sarcomas | |||||||||
7 | 65 | F | Malignant fibrous histiocytoma | High | Thigh | Resection | XRT | AWD after 16 mo | |
8 | 65 | F | Malignant fibrous histiocytoma* | High | Deltoid | Resection | Chemo | DWD after 2 mo | |
9 | 88 | F | Malignant fibrous histiocytoma | High | Leg | Resection | None | AWD after 22 mo | |
10 | 36 | F | Spindle cell sarcoma | Intermediate | Pelvis | Resection | DM | None | CDFS for 10 mo |
11 | 34 | M | Spindle cell sarcoma | Low | Deltoid | Resection | D5S107 | None | CDFS for 15 mo |
12 | 56 | F | Liposarcoma (recurrence) | Low | Thigh | Resection | None | CDFS for 25 mo | |
13 | 57 | M | Liposarcoma | High | Arm | Resection | XRT | CDFS for 10 mo | |
14 | 54 | M | Fibrosarcoma | Intermediate | Thigh | Resection | D13S170, DM | None | CDFS for 22 mo |
15 | 77 | F | Neurofibrosarcoma (recurrence) | High | Thigh | Resection | D11S861, D11S904 | XRT | DWD after 7 mo |
16 | 33 | M | Synovial sarcoma | High | Foot | Amputation | Chemo | CDFS for 5 mo |
AWD, alive with disease; CDFS, continuous disease-free survival; Chemo, chemotherapy; DWD, dead with disease; XRT, radiotherapy.
Metastases on presentation.