Table 2.
Data of interest extracted from the included studies
| Information groups | Data retrieved |
|---|---|
| Group 1: General information | Name of the first author |
| The year of publication | |
| Characteristics of living organism used for synthesis of metal NPs (scientific name, common name, family, morphological type, type of microorganism and origin of isolation | |
| Group 2: Data on mode of synthesis of NPs | Biological material |
| Quantity of biological material | |
| Metal source | |
| Extraction solvent | |
| Group 3: Methods used for physical characterization of metal NPs | Shape |
| Size | |
| Size distribution | |
| Silver content | |
| Stability | |
| Structure-crystallinity | |
| Group 4: Data on method used for evaluation antiplasmodial activity of NPs | Study design (in vivo, in vitro) |
| Nature and origin of Plasmodium strain | |
| Negative and positive controls | |
| NPs doses tested | |
| Group 5: Data on physical properties of NPs | Size, shape, color |
| Maximum absorption peak | |
| Aggregation phenomenon | |
| Group 6: Data on antiplasmodial efficacy of NPs and their cytotoxic activity | 50% inhibitory concentration (IC50) and/or percentage parasite growth inhibition |
| Tests used to appraise the NPs toxicity | |
| Side effects recorded |