Table 2.

The most up- and downregulated miRNAs in cancer compared to benign tissue, sorted by logFC

MiRNA	LogFC cancer versus benign	p*
miR-2964a-5p	4.859	6.74E−44
miR-4419b	1.249	1.84E−23
miR-3164	1.146	2.22E−12
miR-K12-5-5p	1.143	2.90E−12
miR-221-5p	0.924	1.51E−17
miR-585	0.920	1.80E−11
miR-342-3p	0.865	1.07E−07
miR-766-5p	0.846	1.77E−10
miR-4478	0.828	1.03E−21
miR-338-5p	0.815	2.64E−12
miR-21-5p	0.703	8.74E−04
miR-342-5p	0.667	3.27E−13
miR-149-3p	0.660	1.46E−08
miR-5196-3p	0.650	6.37E−20
miR-182-5p	0.644	9.59E−08
miR-4644	0.592	8.30E−08
miR-224-3p	0.588	2.81E−11
miR-4768-5p	0.586	2.13E−12
miR-4778-3p	0.565	5.08E−17
miR-4417	0.559	5.72E−05

miR-451a	− 2.647	1.89E−18
miR-143-3p	− 2.096	4.90E−27
miR-99a-5p	− 2.093	3.52E−24
miR-4328	− 2.090	1.42E−27
miR-145-5p	− 2.061	3.39E−29
miR-205-5p	− 2.027	1.45E−12
miR-195-5p	− 2.023	8.11E−25
miR-125b-5p	− 1.970	8.70E−14
miR-126-3p	− 1.862	1.89E−25
miR-26b-5p	− 1.837	1.01E−24
miR-4324	− 1.651	1.04E−25
miR-29a-3p	− 1.592	3.44E−12
miR-10b-5p	− 1.483	6.87E−24
miR-30b-5p	− 1.452	1.03E−15
let-7d-5p	− 1.450	6.25E−21
miR-130a-3p	− 1.406	4.80E−19
miR-199b-5p	− 1.400	1.84E−23
miR-29b-3p	− 1.339	1.56E−14
miR-199a-3p	− 1.316	2.13E−13
miR-24-3p	− 1.287	7.37E−18

Log fold change (logFC) values are calculated, based on the log2 transformed intensity values (Hy3) by microarray analyses, comparing breast cancer to benign tissue controls. The 20 most upregulated and the 20 most downregulated miRNAs, sorted by highest and lowest logFC, respectively, are presented

* False discovery rate (FDR) adjusted p-value. E indicates exponential number