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ROC curve analysis of serum concentrations from patients with CRC and controls. (A) ROC curves of S100A9, TNC, CEA and CA19-9 levels as screening biomarkers of CRC. (B) ROC curves of S100A9, TNC, CEA and CA19-9 levels as biomarkers differentiating between CRC and BCD. (C) The AUC performance of the following combinations of serum concentrations: S100A9 and TNC; CEA and CA19-9; and S100A9, TNC and CEA.
