Table 3.

Multivariate Cox regression analyse for OS.

	Training set								Validation set								Combined set
Characteristics	HR		95%CI				P		HR		95%CI				P		HR		95%CI				P
Age(years)							0.644
<60	1.00
≥60	1.129		0.675-1.886
Tumor size(cm)							0.425								0.024								0.042
<5	1.00								1.00								1.00
≥5	1.257		0.717-2.202						1.784		1.079-2.949						1.455		1.015-2.088
Surgical procedure															0.959								0.730
Proxima gastrectomy									1.00								1.00
Total gastrectomy									1.012		0.650-1.574						1.057		0.772-1.447
PLR							0.612								0.871								0.327
<110	1.00								1.00								1.00
≥110	1.160		0.654-2.058						1.050		0.580-1.900						1.238		0.807-1.900
LMR							0.052								0.113								0.271
<3.25	1.00								1.00								1.00
≥3.25	0.600		0.359-1.005						0.674		0.414-1.098						0.820		0.576-1.167
SII							0.320								0.715								0.863
<451	1.00								1.00								1.00
≥451	1.403		0.720-2.736						1.105		0.646-1.890						1.040		0.668-1.618
pTNM stage							<0.001								<0.001								<0.001
I	1.00								1.00								1.00
II	3.682		0.834-16.250				0.085		5.045		1.155-22.038				0.031		2.774		1.079-7.134				0.034
III	11.304 2.637-48.455						0.001		10.634 2.489-45.433						0.001		6.118		2.418-15.478				<0.001
F-NLR							0.007								0.003								0.002
0	1.00								1.00								1.00
1	3.394		1.417-8.129				0.006		2.860		1.278-6.397				0.011		1.921		1.124-3.283				0.017
2	4.591		1.776-11.866				0.002		4.432		1.880-10.450				0.001		2.764		1.559-4.900				0.001

OS: overall survival; HR: hazard ratio; CI: confidence interval; UGC: upper gastric cancer; AEG: adenocarcinoma of esophagogastric junction; PLR: platelet-lymphocyte ratio; LMR: lymphocyte-monocyte ratio; SII:(SII=N×P/L), which was based on neutrophil (N), platelet (P) and lymphocyte (L) counts; F-NLR: combination of fibrinogen concentration and neutrophil-lymphocyte ratio.