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. 2019 Aug 29;10(22):5397–5403. doi: 10.7150/jca.32875

Figure 4.

Figure 4

Effects of the p38 inhibitor SB203580 and oxymatrine on cell invasion and MMP-2/-9 expression in MHCC97H cells. (A) MHCC97H cells were pretreated with SB203580 and then incubated in the presence or absence of oxymatrine (0.1 mg/ml) for 24 h. Cellular invasiveness was measured using the transwell chamber invasion assay. (B) The percent invasion rate was expressed as a percentage of control. (C, D) The protein levels of MMP-2/-9 in MHCC97H cells treated with various concentrations of oxymatrine (0, 0.1, 0.2 and 0.3 mg/ml) and analyzed with western blotting. Values represent the means ± SD of three independent experiments. *p< 0.05 and **p< 0.01 vs control group.