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Oxymatrine inhibits the growth of tumor in MHCC97H xenografts. (A) Growth curves presented the volumes of tumor in BALB/c nude mice treated with PBS or oxymatrine. (B) The weight of tumor was measured in each group when the experiment was over. (C)The expression level of MMP-2 and MMP-9 in tumor tissues was detected by western blot. (D) The expression level of p38 and p-p38 in tumor tissues was detected by western blot. *P<0.05 vs PBS (control). PBS, phosphate-buffered saline.
