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. 2019 Aug 20;42(5):1957–1971. doi: 10.3892/or.2019.7283

Figure 5.

Figure 5.

Effects of miR-378a-3p on the proliferation and apoptosis of U87MG cells by targeting TSPAN17. (A) Cell proliferation was analyzed by an MTT assay after transfection; *P<0.05 vs. the mimic-NC control; **P<0.05 vs. anta-NC; †P<0.05 vs. antagomir; ^P<0.05 vs. si-NC; #P<0.05 vs. anta + si; &P<0.05 vs. si-TSPAN17. (B and C) Apoptosis rates were evaluated by flow cytometry after transfection. Data are presented as mean ± standard deviation. All the data are representative of five independent experiments (n=5). FITC, fluorescein isothiocyanate; PI, propidium iodide; miR, microRNA; mimic-NC, miR-378a-3p mimic negative control; mimic, miR-378a-3p mimic; anta-NC, antagomir negative control; anta, antagomir, miR-378a-3p antagomir; si-NC, small interfering RNA negative control; TSPAN17, tetraspanin 17; si-TSPAN17, TSPAN17 small interfering RNA; anta + si, miR-378a-3p antagomir + TSPAN17 small interfering RNA.