Table II.
Multivariate analysis of miR-378a-3p and Tspan17 levels in patients with glioblastoma multiforme.
| miR-378a-3p expression | TSPAN17 expression | |||||
|---|---|---|---|---|---|---|
| Low level (≤median) n (%) | High level (>median) n (%) | Adjusted OR (95% CI) | Low level (≤median) n (%) | High level n (%) | Adjusted OR (95% CI) | |
| WHO grade | ||||||
| I–II | 2 (3.7) | 5 (9.4) | 2.24 (1.54–4.02) | 6 (11.3) | 7 (13.2) | 1.58 (0.98–4.21) |
| III | 23 (43.4) | 2 (3.7) | 16.19 (12.36–28.21) | 5 (9.4) | 10 (18.8) | 14.11 (9.45–29.2) |
| IV | 21 (39.6) | 0 (0) | 21.15 (12.31–31.58) | 1 (1.8) | 24 (45.2) | 10.34 (5.01–23.95) |
| Tumor size (cm) | ||||||
| <5 | 12 (22.6) | 6 (11.3) | 1.82 (1.33–5.01) | 7 (13.2) | 22 (41.5) | 1.23 (0.73–6.49) |
| ≥5 | 34 (64.1) | 1 (1.8) | 42.03 (28.93–57.38) | 5 (9.4) | 19 (35.8) | 1.49 (0.87–3.97) |
Values in bold indicate P<0.05. 95% CI, confidence interval, miR, microRNA; OR, odds ratio; TSPAN17, tetraspanin 17.