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. 2019 Sep 15;200(6):751–759. doi: 10.1164/rccm.201812-2348OC

Figure 1.

Figure 1.

The 18 prespecified severity-graded definitions of bronchopulmonary dysplasia (BPD). Definitions 1–3 establish the initial framework. Key components of the definition evaluated in each subset are highlighted by the red boxes. All infants treated with head box oxygen are included with those receiving nasal cannula (NC) at ≤2 L/min flow. The mode of respiratory support and FiO2 were recorded as the highest level administered at 36 weeks’ postmenstrual age (PMA). Any temporary increases in FiO2 for desaturation events, apnea, bradycardia, or procedures were disregarded if the infant returned to the previous FiO2 within 2 hours. Supplemental oxygen administered only during feedings was not included for infants who did not receive oxygen therapy at other times during the day. nCPAP = nasal continuous positive airway pressure; NIPPV = nasal intermittent positive pressure ventilation; PPV = positive pressure ventilation.