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. 2019 Oct;61(4):450–458. doi: 10.1165/rcmb.2018-0220OC

Figure 4.

Figure 4.

CDHR3 rs6967330 genotype impacts protein expression and rhinovirus C (RV-C) infection in human BEC-ALI cultures. (A) CDHR3 (∼100 kD) protein expression in A/A, A/G, and G/G genotypes of differentiating BEC-ALI cultures on Days 7, 14, 21, and 28. (B) Quantification of CDHR3 protein expression signal intensity from Western blots shown in A. (C) CDHR3 mRNA expression in BEC-ALI cultures with A/A, A/G, and G/G genotypes over a 28-day differentiation time period (n = 3). (D) RV-C15 binding (1 h postinfection) and (E) RV-C15 RNA progeny yield (24 h postinfection) in A/A, A/G, and G/G genotypes of ALI cultures over 28-day differentiation period (n = 3). ‡P < 0.05 between donors that have A/A and G/G genotypes only; *P < 0.05 and **P < 0.01.